Book Your Private Bone Profile Blood Test

Your bones are living tissue that is constantly being broken down and rebuilt. The correct balance of minerals and proteins can be disrupted through dietary or hormonal changes, causing reduced bone density and strength.

The Bone Profile Blood Test evaluates essential minerals and proteins involved in producing and maintaining healthy bones and teeth.

A Bone Profile Blood Test can be requested for many reasons:

• To diagnose and monitor disorders of the bone (e.g. osteomalacia, Paget’s disease, bony metastases)
• To diagnose and monitor cases of hypercalcaemia or hypercalcaemia
• To investigate unexplained symptoms, such as fatigue or pain

Medical conditions that weaken the strength of bones include:

• Osteoporosis - a bone disease that thins and weakens the bones, increasing the risk of fracture.
• Paget's Disease of Bone – affects bone turnover and rebuilding, causing faster bone replacement and leading to brittle bone tissue and bone pain.
• Bone cancer - causes abnormal bone tissue formation. This leads to bones being thick, brittle, and weak.
• Parathyroid and liver problems – can also be identified with the Bone Profile Blood Test.
• A Bone Profile Blood Test can detect a person’s risk of bone disease and/or cancer.

The Bone Profile Test is recommended if you:

• Are over 50 years old, particularly if you are a woman.
• Are an Asian or Caucasian woman, as these groups are at a higher risk of osteoporosis.
• Are currently experiencing menopause, which can lead to deficiencies.
• Are a smoker.
• Regularly consume alcohol or engage in binge drinking.
• Have a family history of osteoporosis.
• Have a history of fractures, indicating potential bone strength issues.
• Have had gastrointestinal diseases (e.g., IBS).

Certain medications can increase the risk of osteoporosis, including:

• Steroids
• Acid suppressing medication (proton pump inhibitors)
• Depression and anxiety medication
• Medication for epilepsy (anticonvulsants)

The blood profile measures four main minerals . These are:

• Calcium - is a critical mineral to support your bone health. Normal levels of calcium are 2.2-2.6 mmol/L.
• Albumin - Decreased levels of albumin are linked to decreased bone density, such as that caused by osteoporosis. The normal range is 35-50 g/L.
• Phosphates - contain phosphorus which is a mineral crucial for bone growth. The normal range is between 0.74 and 1.4 mmol/L.
• Alkaline phosphatase (ALP) - is an enzyme present in bone and liver cells, used for detecting bone or liver disorders. The normal range for this enzyme is 30-130 u/L in adults.

There is no preparation needed for the test. However, if you take vitamin D or calcium supplements they may affect your test results. You may wish to discontinue these supplements before the test.

The blood test itself is very simple. The blood sample is taken from a vein in your arm, as opposed to using a finger-prick blood test, because results tend to be more accurate this way. The test is relatively painless, except for a slight pricking sensation as the phlebotomist inserts the needle. After the blood is drawn into a vial, the blood sample is then sent to a laboratory for testing.

Need help? Call free on

0800 652 2183 to speak to one of our team.